tRanslatome: an R/Bioconductor package to portray translational control

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tRanslatome: an R/Bioconductor package to portray translational control

UNLABELLED High-throughput technologies have led to an explosion of genomic data available for automated analysis. The consequent possibility to simultaneously sample multiple layers of variation along the gene expression flow requires computational methods integrating raw information from different '-omics'. It has been recently demonstrated that translational control is a widespread phenomeno...

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15 صفحه اول

Principles of translational control: an overview.

Translational control plays an essential role in the regulation of gene expression. It is especially important in defining the proteome, maintaining homeostasis, and controlling cell proliferation, growth, and development. Numerous disease states result from aberrant regulation of protein synthesis, so understanding the molecular basis and mechanisms of translational control is critical. Here w...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2013

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/btt634